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Premature human engineering
The news buzz alive with excitement about human genome editing, even human germline engineering. Successful germline engineering requires (1) a technology for editing DNA safely and (2) knowledge of what to edit and how to edit based on understanding the underlying biology. We are approaching (1), which is the easier part; we do not have (2), … Continue reading Premature human engineering
Increasingly direct evidence
The results in our Cell report are particularly satisfying to me since they bring clarity to a puzzle that I have pursued for almost a decade. The puzzle started with an observation that I made while a graduate student in the Botstein laboratory at Princeton University. I studied the transcriptional responses of yeast cells growing … Continue reading Increasingly direct evidence